TerraPower Isotopes has broken ground on a production facility for the radioisotope Actinium-225, valued at over $450 million, in Pennsylvania, USA, intended for cancer treatment.
The Bellwether Laboratory complex is being built in the Bellwether District, a redevelopment site on a former oil refinery in South Philadelphia. Spanning over 23,200 square meters, the facility will operate according to U.S. Current Good Manufacturing Practice (cGMP) standards.
The project focuses on producing Ac-225, a radioisotope used in research and trials for Targeted Alpha Therapy—a cancer treatment method that delivers radiation directly to diseased cells while minimizing impact on surrounding healthy tissue.
TerraPower stated that Bellwether Laboratory will be the world’s largest Ac-225 production facility once operational. Along with its existing facility in Everett, Washington, the company’s production capacity is expected to increase 20-fold to address the supply shortage of radioisotopes for cancer drug research and development.
Pennsylvania is directly supporting the project through a $10 million investment along with economic development, infrastructure, and tax incentives for the high-tech sector. According to the state’s economic development agency, TerraPower selected Philadelphia after surveying more than 350 sites in various U.S. cities.
In addition to the technological and biomedical aspects, the project is currently raising capital through the EB-5 immigrant investor program via the CanAm Regional Center. This program allows foreign investors to obtain U.S. permanent residency by participating in projects that meet job creation requirements set by the U.S. government.
CanAm Enterprises is one of the longest-standing regional centers in the field, with over 30 years of experience in the U.S. and Canada. The company has sponsored 78 projects, raised more than $4 billion in EB-5 capital, and repaid over $2.5 billion to investors.
This article was first published on May 27, 2026, on VnExpress and can be viewed here.
For more information, contact fle@canamenterprises.com or info@canamenterprises.com.
